Russian scientists plans to present the world’s first artificial human kidney and thyroid gland by 2018
3D Bioprinting Solutions, one of Russia’s leading biotechnological laboratories, has officially announced the design of the world’s first organ construct of thyroid gland, which took place with use of FABION, Russia’s first bioprinter.
According to Vladimir Mironov, head of the laboratory, the new construct is comprised of several types of tissue and has its own vascularization. He has also added that the new development is designed for the implantation to test animals, however by 2018 scientists hope to complete the design of its analogue, that will be suitable for human transplantation.
The new technology was developed by scientists of 3D Bioprinting Solutions and is considered as one of the alternatives to stem cells. According to scientists, its use should help to solve a problem of a shortage of donor organs for transplantation in due course.
According to Vladimir Mironov, the new technology is produced by a new bioprinter, which is a robotic device, that allows to accurately allocate biomaterial, including living cells in layers in three-dimensional space. It was jointly designed by Russian scientists and scientists from the University of Vienna.
Mironov has also added that the new technology is based on the use of tissue spheroids (which are produced on the basis of microfluidics technology) as building blocks.
According to scientists of 3D Bioprinting Solutions, at present there are about 12 commercial bioprinters available globally, however the Russian model is probably the world’s most currently advanced, which is mainly due to its multifunctionality.
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As part of the plans of 3D Bioprinting Solutions, is the production of human kidney, the most demanded organ for transplantation by 2018.
Scientists of the laboratory believe that they will be able to complete kidney design already during the next three years, despite the predictions of some Western scientists, according to which the production of the world’s first human kidney on the basis of bioprinter will take place no sooner than by 2030.
In the meantime, Russia’s leading doctors and scientists in the field of medicine believe that the technology will be suitable for the use in clinical practice.
According to Andrey Polyakov, head of department of neck tumors and microsurgery of the Moscow Medical Radiological Research Center, the produced artificial thyroid gland has its own vessels, both arterial and venous, which can provide blood flow and nutrition, as well as transportation of produced hormones for the body.
This is not the first successful development of Russian scientists in the field of tissue engineering, in 2013, in accordance with an initiative of Peter Glybochko, head of I.M. Sechenov First Moscow State Medical University, (Russia’s oldest and the largest national medical higher educational institution), a group of the university’s scientists had successfully created and transplanted a fragment of bioengineering urethra to a patient suffered from ankylurethria.
Eugene Gerden is an international free-lance writer, based in St. Petersburg, who specializes on writing in the field of mining, metals and rare earth metals. ... <Read more about Eugene Gerden>