InvestorIntel and friends offer condolences to Bernard Tourillon
The editorial board of InvestorIntel is extending heartfelt condolences to Mr Bernard Tourillon and his family for the passing of their only son Sebastien C. Tourillon, 19, after a long battle with cystic fibrosis.
Bernard Tourillon is a dear friend of InvestorIntel and we share his sorrows.
Mr. Tourillon will be taking a temporary leave of absence from his position as Chairman and CEO of HPQ Silicon Resources Inc. (TSXV: HPQ).
Parents aren’t supposed to survive their children, yet one in every 3,600 children born in Canada has cystic fibrosis. More than 4,100 Canadian children, adolescents, and adults with cystic fibrosis attend specialized cystic fibrosis clinics.
Cystic fibrosis is the most common fatal genetic disease affecting Canadian children and young adults. To date, there is no cure.
Cystic fibrosis causes various effects on the body, but mainly affects the digestive system and lungs. It is devastating to victims and their family.
Get our daily investorintel update
The degree of cystic fibrosis severity differs from person to person, however, the persistence and ongoing infection in the lungs, with destruction of lungs and loss of lung function, will eventually lead to death in the majority of people with cystic fibrosis.
Children have succumbed to the disease for thousands of years but because it is a genetic disease, its cause has been misunderstood until the 1940s.
At first it was a thought to be a curse. European folklore from the Middle Ages warned “woe is the child who tastes salty from a kiss on the brow, for he is cursed, and soon must die”. As early as 1595 medical texts linked salty skin and damage to the pancreas with death in childhood by infants who were “hexed” or “bewitched”.
To their credit, people in Middle Age were unaware of the principle of genetics and even less so of genetic diseases. The principles of Mendelian inheritance emerged in the 1860s when Gregor Johann Mendel, an Austrian monk conducted simple hybridization experiments with 5,000 pea plants he had planted in the garden of his monastery From these experiments, he induced two generalizations, which later became known as Mendel’s Principles of Heredity or Mendelian inheritance.
In 1938, the American Pathologist Dr. Dorothy Andersen provided the first description of the disorder in the medical literature, calling the disease “cystic fibrosis of the pancreas” based on her autopsy findings of children that died of malnutrition.
During a heat wave in the summer of 1948, Dr. Paul di Sant’Agnese observed infants presenting with dehydration to a New York City emergency room. This led to his discovery that the sweat of children with cystic fibrosis had abnormally high concentrations of salt, and validated the ancient folklore of the disease. In the 1980s, the protein defect was described, and in 1989 the responsible gene (CFTR) was identified and its genetic code was sequenced (Source).
Typical complications caused by cystic fibrosis are:
- Difficulty digesting fats and proteins
- Malnutrition and vitamin deficiencies because of inability to absorb nutrients
- Progressive lung damage from chronic infections and aberrant inflammation
- Cystic fibrosis-related diabetes
- Sinus infections
Dr. Luc C. Duchesne is a Speaker and Author with a PhD in Biochemistry. With three decades of scientific and business experience, he has published ... <Read more about Dr. Luc Duchesne>